Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057145 | 1.00 | KIF11 (1.00) | KIF11KCNH2 | |
| SCHEMBL4058441 | 1.00 | KIF11 (1.00) | KIF11KCNH2 | |
| SCHEMBL4061685 | 0.96 | KIF11 (0.92) | KIF11KCNH2 | |
| SCHEMBL6208505 | 0.96 | KIF11 (0.92) | KIF11KCNH2 | |
| SCHEMBL4071558 | 0.95 | KIF11 (0.90) | KIF11KCNH2 | |
| SCHEMBL4060112 | 0.95 | KIF11 (0.90) | KIF11KCNH2 | |
| SCHEMBL4057828 | 0.91 | KIF11 (1.00) | KIF11KCNH2 | |
| SCHEMBL4059959 | 0.91 | KIF11 (0.83) | KIF11KCNH2 | |
| SCHEMBL4061728 | 0.91 | KIF11 (0.83) | KIF11KCNH2 | |
| SCHEMBL4060252 | 0.88 | KIF11 (1.00) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515724-A4 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2005-08-17 | — | — | EP | claimed |
| EP-1515724-A1 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2005-03-23 | — | — | EP | claimed |
| WO-2003105855-A1 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2003-12-24 | — | — | WO | claimed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |