SCHEMBL6205557

SCHEMBL6205557

CN(C)c1ccc(C(=O)c2ccccc2C(=O)O)c(O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.72
SMN1; SMN2 Q16637 3/20 0.72
MEN1 O00255 2/20 0.72
L3MBTL1 Q9Y468 1/20 0.72
ALDH1A1 P00352 5/20 0.65
GAA P10253 2/20 0.65
KDM4E B2RXH2 1/20 0.65
POLB P06746 1/20 0.65
HPGD P15428 3/20 0.51
NPC1 O15118 2/20 0.51
TP53 P04637 2/20 0.51
MAPT P10636 2/20 0.51
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 1/20 0.47
CDC25B P30305 3/20 0.47
CDC25A P30304 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KCNH2 Q12809 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29570529 1.00 KMT2A (0.72) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL22938991 0.90 MEN1 (0.58) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL22939380 0.89 KMT2A (0.58) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL22938966 0.89 HPGD (0.57) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL22939649 0.87 ALDH1A1 (0.64) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL22939013 0.86 ALDH1A1 (0.61) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL9010008 0.85 KMT2A (0.65) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL9618590 0.85 KMT2A (0.78) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL8012544 0.85 KMT2A (0.57) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1
SCHEMBL11842816 0.85 MEN1 (0.53) KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020065319-A1 COLOUR FORMING COMPOSITION DATALASE LTD. (GB) 2020-04-02 WO claimed
WO-2020065317-A1 COLOUR FORMING COMPOSITIONS DATALASE LTD. (GB) 2020-04-02 WO claimed
WO-2020065321-A1 COLOUR FORMING COMPOSITIONS DATALASE LTD. (GB) 2020-04-02 WO claimed
WO-2020065320-A1 COLOUR FORMING COMPONENTS AND COMPOSITIONS DATALASE LTD. (GB) 2020-04-02 WO claimed
EP-2410974-B1 SUNSCREEN COMPOSITION COMPRISING HYDROXYAPATITE AS PHYSICAL SOLAR FILTER KALICHEM ITALIA S R L (IT) 2017-05-24 EP claimed
JP-57005757-A None JP disclosed
JP-60040165-A None JP disclosed
JP-59062666-A None JP disclosed
JP-11228578-A None JP disclosed
JP-57195155-A None JP disclosed
JP-56109252-A None JP disclosed
JP-57177058-A None JP disclosed
JP-S56109252-A PRODUCTION OF FLUORAN DERIVATIVE FUJI PHOTO FILM CO LTD 1981-08-29 JP disclosed
US-4260776-A PYRAZOLONE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4110343-A Bisfluoran chromogenic compounds, preparation thereof, and pressure-sensitive copy systems employing same CHAMPION INTERNATIONAL CORPORATION (US) 1978-08-29 US disclosed
US-4052398-A DIAZARHODAMINE-LACTONES, THEIR MANUFACTURE AND THEIR USE AS DYE INTERMEDIATES FOR COPYING PROCESSES BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-4012419-A Bisfluoran chromogenic compounds, preparation thereof, and pressure-sensitive copy systems employing same CHAMPION INTERNATIONAL CORPORATION (US) 1977-03-15 US disclosed
US-3989716-A Pyrrylfluoran compounds THE MEAD CORPORATION (US) 1976-11-02 US disclosed
US-3988492-A Pressure sensitive copy paper employing pyrazoloxanthene compounds THE MEAD CORPORATION (US) 1976-10-26 US disclosed
US-3985930-A Cyclopolymethylenefluoran compounds THE MEAD CORPORATION (US) 1976-10-12 US disclosed