Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 10/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.52 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205720 | 1.00 | MRGPRX4 (0.63) | MRGPRX4MAOBMAOARAB9ASMN1; SMN2 | |
| SCHEMBL6205725 | 1.00 | MRGPRX4 (0.63) | MRGPRX4MAOBMAOARAB9ASMN1; SMN2 | |
| SCHEMBL6950492 | 0.89 | NR4A2 (0.67) | MRGPRX4MAOBMAOAPKMNR4A2 | |
| SCHEMBL6950489 | 0.89 | NR4A2 (0.67) | MRGPRX4MAOBMAOAPKMNR4A2 | |
| SCHEMBL15563733 | 0.87 | MAOB (0.60) | MAOBRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL15563734 | 0.87 | MAOB (0.60) | MAOBRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL6951282 | 0.85 | NR4A2 (0.70) | MRGPRX4MAOBMAOARAB9APKM | |
| SCHEMBL6951279 | 0.85 | NR4A2 (0.70) | MRGPRX4MAOBMAOARAB9APKM | |
| SCHEMBL6946121 | 0.84 | MAOB (0.66) | MAOBMAOANR4A2SMPD1PTPN1 | |
| SCHEMBL6946117 | 0.84 | MAOB (0.66) | MAOBMAOANR4A2SMPD1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |