Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4361996 | 0.99 | KDM4E (0.45) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL4951613 | 0.95 | KDM4E (0.55) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL4952242 | 0.87 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL4375482 | 0.84 | HSPB1 (0.43) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4955575 | 0.82 | KDM4E (0.45) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL4361883 | 0.81 | CYP19A1 (0.35) | KMT2ACYP19A1 | |
| SCHEMBL4951920 | 0.80 | MAPT (0.40) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL4360433 | 0.79 | SLC8A1 (0.52) | KDM4EMEN1KMT2AALDH1A1BRCA1 | |
| SCHEMBL4359022 | 0.78 | CYP19A1 (0.41) | ALDH1A1HSD17B10CYP19A1 | |
| SCHEMBL4952892 | 0.77 | HSPB1 (0.41) | KDM4EMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583759-A1 | PYRIDINE DERIVATIVES USEFUL FOR INHIBITING SODIUM/CALCIUM EXCHANGE SYSTEM | ORION CORPORATION (FI) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004063191-A1 | PYRIDINE DERIVATIVES USEFUL FOR INHIBITING SODIUM/CALCIUM EXCHANGE SYSTEM | ORION CORPORATION (FI) | 2004-07-29 | — | — | WO | disclosed |