Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LIFR | P42702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205799 | 1.00 | MRGPRX4 (0.48) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6205485 | 1.00 | MRGPRX4 (0.48) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6207013 | 0.89 | MRGPRX4 (0.42) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6207009 | 0.89 | MRGPRX4 (0.42) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6204938 | 0.89 | MRGPRX4 (0.42) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6206165 | 0.84 | SPHK2 (0.50) | MRGPRX4NR4A2NPC1RAB9ANR4A1 | |
| SCHEMBL6206166 | 0.84 | SPHK2 (0.50) | MRGPRX4NR4A2NPC1RAB9ANR4A1 | |
| SCHEMBL6206160 | 0.84 | SPHK2 (0.50) | MRGPRX4NR4A2NPC1RAB9ANR4A1 | |
| SCHEMBL6204484 | 0.83 | NR4A2 (0.54) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6206142 | 0.83 | NR4A2 (0.54) | MRGPRX4NR4A2NPC1RAB9ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |