Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207009 | 1.00 | MRGPRX4 (0.42) | MRGPRX4NR4A2XDHNPC1RAB9A | |
| SCHEMBL6204938 | 1.00 | MRGPRX4 (0.42) | MRGPRX4NR4A2XDHNPC1RAB9A | |
| SCHEMBL6205801 | 0.89 | MRGPRX4 (0.48) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6205799 | 0.89 | MRGPRX4 (0.48) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6205485 | 0.89 | MRGPRX4 (0.48) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL6206005 | 0.84 | FFAR1 (0.49) | XDHNPC1RAB9AALDH1A1SPHK2 | |
| SCHEMBL6206002 | 0.84 | FFAR1 (0.49) | XDHNPC1RAB9AALDH1A1SPHK2 | |
| SCHEMBL6205999 | 0.84 | FFAR1 (0.49) | XDHNPC1RAB9AALDH1A1SPHK2 | |
| SCHEMBL6947812 | 0.77 | MEN1 (0.56) | NR4A2ALDH1A1HPGDGPBAR1 | |
| SCHEMBL6947809 | 0.77 | MEN1 (0.56) | NR4A2ALDH1A1HPGDGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |