Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ATP1A1 | P05023 | 5/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 5/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 5/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 5/20 | 0.39 |
| ▸ | ATP4A | P20648 | 5/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 5/20 | 0.39 |
| ▸ | ATP4B | P51164 | 5/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 5/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 5/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | WDR5 | P61964 | 3/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360274 | 0.89 | CYP2C9 (0.58) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5370507 | 0.86 | CYP2C9 (0.57) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL6503400 | 0.78 | CYP2C9 (0.39) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL6505216 | 0.77 | BRS3 (0.52) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5360264 | 0.76 | CYP2C9 (0.56) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5370494 | 0.74 | CYP2C9 (0.55) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5763051 | 0.74 | CYP2C9 (0.41) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL6478128 | 0.73 | CYP2C9 (0.58) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| Omeprazole Sulfone SCHEMBL4950986 | 0.72 | CYP2C9 (1.00) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5368644 | 0.72 | CYP2C9 (0.41) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556371-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | Winston Pharmaceuticals LLC (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004009583-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | GARST MICHAEL E (US) | 2004-01-29 | — | — | WO | disclosed |