Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 5/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 5/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 5/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 5/20 | 0.38 |
| ▸ | ATP4A | P20648 | 5/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 5/20 | 0.38 |
| ▸ | ATP4B | P51164 | 5/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 5/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 5/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | WDR5 | P61964 | 3/20 | 0.36 |
| ▸ | BRS3 | P32247 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503395 | 0.89 | CYP2C9 (0.37) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5368139 | 0.89 | CYP2C9 (0.41) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5370557 | 0.88 | CYP2C9 (0.40) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL6505216 | 0.85 | BRS3 (0.52) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5763051 | 0.82 | CYP2C9 (0.41) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5364408 | 0.81 | CYP2C9 (0.39) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5369395 | 0.80 | CYP2C9 (0.35) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5370615 | 0.80 | CYP2C9 (0.37) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5368644 | 0.80 | CYP2C9 (0.41) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5366930 | 0.80 | CYP2C9 (0.39) | CYP2C9ATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182101-A1 | Prodrugs of proton pump inhibitors | GARST MICHAEL (US) | 2005-08-18 | — | — | US | disclosed |
| US-20050143423-A1 | Prodrugs of proton pump inhibitors background of the invention | GARST MICHAEL (US) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143423-A1 | Prodrugs of proton pump inhibitors background of the invention | ABCB11, SLC10A2, SI | CYP2C9 49/4885ATP1A1 42/4885ATP1B1 76/4885 |
| US-20050182101-A1 | Prodrugs of proton pump inhibitors | ABCB11, SLC10A2, SI | CYP2C9 83/4885ATP1A1 33/4885ATP1B1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.