SCHEMBL6205906

SCHEMBL6205906

CCc1ccc(CN2CCC(NC(=O)CNC(=O)c3cc(OC(F)(F)F)ccc3N)C2)cc1

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5438844 0.92 CCR2 (0.85) CCR2
Hydrochloric Acid SCHEMBL5438847 0.92 CCR2 (0.85) CCR2
SCHEMBL4847944 0.88 CCR2 (0.81) CCR2
SCHEMBL4847958 0.88 CCR2 (0.81) CCR2
SCHEMBL6206217 0.88 CCR2 (1.00) CCR2
SCHEMBL4840803 0.87 CCR2 (0.85) CCR2
SCHEMBL4840793 0.87 CCR2 (0.85) CCR2
SCHEMBL8177859 0.86 CCR2 (0.70) CCR2
SCHEMBL4847793 0.85 CCR2 (0.82) CCR2
SCHEMBL4844491 0.85 CCR2 (0.82) CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535909-A2 Cyclic amine derivatives and their use as drugs TEIJIN LIMITED (JP) 2005-06-01 EP claimed
US-6451842-B1 Cyclic amine derivatives and their use as drugs DUPONT PHARMACEUTICALS COMPANY 2002-09-17 US claimed