Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336539 | 0.88 | RAB9A (0.63) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL9488109 | 0.85 | CA12 (0.66) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL3586442 | 0.85 | RAB9A (0.53) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL29918535 | 0.84 | MAPT (0.64) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL3910111 | 0.83 | EGFR (0.61) | RAB9AMAPTSMN1; SMN2TSHRCA12 | |
| SCHEMBL25383176 | 0.83 | CA12 (0.55) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL28813537 | 0.82 | RAB9A (0.51) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL28771192 | 0.82 | RAB9A (0.51) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL28344398 | 0.82 | RAB9A (0.53) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL5924878 | 0.82 | F2RL3 (0.53) | RAB9ACYP1A2NPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| EP-1503997-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097617-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |