Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206646 | 0.77 | ELANE (0.43) | ELANEPARP10NSD2TDP1L3MBTL1 | |
| SCHEMBL6205992 | 0.77 | ELANE (0.43) | ELANEPARP10NSD2TDP1L3MBTL1 | |
| SCHEMBL6204752 | 0.77 | ELANE (0.52) | ELANEPARP10NSD2TDP1L3MBTL1 | |
| SCHEMBL6206634 | 0.77 | ELANE (0.43) | ELANEPARP10NSD2TDP1L3MBTL1 | |
| SCHEMBL9562937 | 0.77 | ELANE (0.52) | ELANEPARP10NSD2TDP1L3MBTL1 | |
| SCHEMBL6206058 | 0.74 | TSHR (0.47) | ELANETDP1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL4607748 | 0.74 | CES1 (0.42) | TDP1L3MBTL1HSD17B10F2LMNA | |
| SCHEMBL6207375 | 0.74 | TSHR (0.47) | ELANETDP1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL6206053 | 0.73 | ELANE (0.43) | ELANEPARP10NSD2TDP1L3MBTL1 | |
| SCHEMBL6206048 | 0.73 | ELANE (0.43) | ELANEPARP10NSD2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |