⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827498 | 0.72 | — | — | |
| SCHEMBL29620 | 0.72 | — | — | |
| Water SCHEMBL27460201 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL2702442 | 0.69 | — | — | |
| SCHEMBL44721 | 0.67 | — | — | |
| SCHEMBL45172 | 0.67 | — | — | |
| SCHEMBL9600 | 0.67 | — | — | |
| SCHEMBL1567546 | 0.67 | — | — | |
| SCHEMBL277951 | 0.67 | — | — | |
| SCHEMBL11878755 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929553-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2005-03-16 | — | — | EP | claimed |
| US-6251911-B1 | Pyrimidine derivatives and processes for the preparation thereof | NOVARTIS AG (CH) | 2001-06-26 | — | — | US | claimed |
| EP-0819129-B1 | PYRAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2000-08-02 | — | — | EP | claimed |
| EP-0929553-A1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Novartis AG (CH) | 1999-07-21 | — | — | EP | claimed |
| WO-1998014450-A1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 1998-04-09 | — | — | WO | claimed |
| EP-0265050-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1991-05-15 | — | — | EP | claimed |
| EP-0265050-A1 | Mitomycin derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-04-27 | — | — | EP | claimed |
| US-4564678-A | ANTISECRETARY AGENTS | KOTOBUKI SEIYAKU COMPANY, LIMITED (JP) | 1986-01-14 | — | — | US | claimed |
| EP-0929553-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2005-03-16 | — | — | EP | disclosed |
| EP-0819129-B1 | PYRAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2000-08-02 | — | — | EP | disclosed |
| EP-0929553-A1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Novartis AG (CH) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014450-A1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 1998-04-09 | — | — | WO | disclosed |
| EP-0265050-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4820824-A | ANTITUMOR AGENTS, BACTERICIDES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1989-04-11 | — | — | US | disclosed |
| EP-0265050-A1 | Mitomycin derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-04-27 | — | — | EP | disclosed |
| US-4564678-A | ANTISECRETARY AGENTS | KOTOBUKI SEIYAKU COMPANY, LIMITED (JP) | 1986-01-14 | — | — | US | disclosed |