Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403040 | 0.82 | HTR2A (0.32) | KDM4E | |
| SCHEMBL4403038 | 0.78 | KDM4E (0.37) | KDM4E | |
| SCHEMBL4403044 | 0.78 | KDM4E (0.37) | KDM4E | |
| SCHEMBL6744858 | 0.78 | PDCD1 (0.34) | MEN1KMT2A | |
| SCHEMBL4404755 | 0.77 | MERTK (0.37) | KDM4EMEN1KMT2A | |
| SCHEMBL4404752 | 0.77 | MERTK (0.37) | KDM4EMEN1KMT2A | |
| SCHEMBL4395951 | 0.75 | PDGFRB (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL4395948 | 0.75 | PDGFRB (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL29940738 | 0.68 | MAPT (0.34) | KDM4EMEN1KMT2A | |
| SCHEMBL20569821 | 0.68 | MAPT (0.34) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549651-A1 | KINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011465-A1 | KINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-05 | — | — | WO | disclosed |