Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 9/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255757 | 0.84 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4495706 | 0.81 | KCNH2 (0.47) | PTPN11KCNH2PIK3CAMTORLTA4H | |
| SCHEMBL1712297 | 0.76 | PDCD1LG2 (0.41) | PTPN11PIK3CAMTOR | |
| SCHEMBL1712303 | 0.76 | PDCD1LG2 (0.41) | PTPN11PIK3CAMTOR | |
| SCHEMBL3373329 | 0.75 | PTPN11 (0.34) | PTPN11KCNH2PIK3CAMTOR | |
| SCHEMBL3372981 | 0.75 | PTPN11 (0.34) | PTPN11KCNH2PIK3CAMTOR | |
| SCHEMBL1723362 | 0.75 | KDM4E (0.36) | KCNH2PIK3CAMTOR | |
| SCHEMBL5266439 | 0.73 | PTPN11 (0.42) | PTPN11KCNH2 | |
| SCHEMBL6630462 | 0.73 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL592229 | 0.72 | MTNR1B (0.35) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583537-A3 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-12-14 | — | — | EP | disclosed |
| EP-1583537-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004002490-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |