Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 6/20 | 0.34 |
| ▸ | CCNC | P24863 | 5/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206362 | 0.86 | KCNH2 (0.41) | KCNH2SLC2A1CDK8 | |
| SCHEMBL4484328 | 0.83 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL13921377 | 0.83 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL4487393 | 0.81 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL13921378 | 0.81 | KCNH2 (0.61) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4484228 | 0.81 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL4497667 | 0.78 | DRD2 (0.39) | KCNH2CDK8CCNCCDK19MAP4K2 | |
| SCHEMBL4497675 | 0.78 | DRD2 (0.39) | KCNH2CDK8CCNCCDK19MAP4K2 | |
| SCHEMBL13934618 | 0.72 | KCNH2 (0.50) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4480929 | 0.72 | HRH3 (0.38) | KCNH2CDK8CCNCCDK19MAP4K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583537-A3 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-12-14 | — | — | EP | claimed |
| EP-1583537-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-10-12 | — | — | EP | claimed |
| WO-2004002490-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | claimed |