Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480529 | 0.84 | IDO1 (0.52) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL6205366 | 0.84 | CA12 (0.47) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL28805376 | 0.80 | IDO1 (0.52) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL9479313 | 0.79 | IDO1 (0.47) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL6205489 | 0.78 | IDO1 (0.44) | IDO1TAAR1HTTALDH1A1MAPT | |
| SCHEMBL6205184 | 0.78 | LMNA (0.43) | IDO1TAAR1ALDH1A1MAPTHPGD | |
| SCHEMBL878976 | 0.78 | IDO1 (0.53) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL6201417 | 0.77 | IDO1 (0.42) | IDO1TAAR1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6206376 | 0.77 | IDO1 (0.48) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL27612089 | 0.77 | IDO1 (0.53) | IDO1TAAR1CHRM2CHRM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |