Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856065 | 0.73 | — | — | |
| SCHEMBL8532162 | 0.66 | — | — | |
| SCHEMBL15791399 | 0.63 | — | — | |
| SCHEMBL8076018 | 0.61 | — | — | |
| SCHEMBL12180911 | 0.60 | — | — | |
| SCHEMBL14654367 | 0.59 | CYP2A6 (0.33) | — | |
| SCHEMBL4671656 | 0.59 | NISCH (0.41) | — | |
| SCHEMBL15630267 | 0.57 | — | — | |
| SCHEMBL2553587 | 0.57 | CCR8 (0.33) | — | |
| SCHEMBL14654530 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501831-A1 | INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091255-A1 | INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-06 | — | — | WO | disclosed |