SCHEMBL14654367

SCHEMBL14654367

CC1CCc2c([nH]c3c2CCC=C3)C1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.33
CYP2A13 Q16696 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8856065 0.72
SCHEMBL4671656 0.68 NISCH (0.41) TSHR
SCHEMBL12180911 0.66
SCHEMBL14652713 0.65
SCHEMBL5674841 0.64 GRIA2 (0.43) ALDH1A1
SCHEMBL14654530 0.62
SCHEMBL19032136 0.62 ALDH1A1 (0.37) CYP2A6CYP2A13ALDH1A1TSHRKMT2A
SCHEMBL8579183 0.62 RB1 (0.63)
SCHEMBL15791399 0.62
SCHEMBL26068499 0.62 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013012298-A1 9H-CARBAZOLE COMPOUNDS AND ELECTROLUMINESCENT DEVICES INVOLVING THEM ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-01-24 WO disclosed