Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 7/20 | 0.46 |
| ▸ | CES1 | P23141 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208804 | 0.81 | TSHR (0.48) | ALDH1A1MAPTKMT2ACES2CES1 | |
| SCHEMBL11808597 | 0.79 | MEN1 (0.48) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL11808595 | 0.79 | MEN1 (0.48) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL10962111 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2ACES2 | |
| SCHEMBL10962109 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2ACES2 | |
| SCHEMBL6206515 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ACES2 | |
| SCHEMBL16942397 | 0.77 | MEN1 (0.60) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6206511 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ACES2 | |
| SCHEMBL7644848 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ACES2 | |
| SCHEMBL4739425 | 0.75 | KMT2A (0.50) | ALDH1A1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |