SCHEMBL62068

SCHEMBL62068

Cc1c(N)cc(N)cc1S

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.41
CASP1 P29466 1/20 0.39
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
PIK3CA P42336 1/20 0.32
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP7 P55210 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24718510 0.86 ALDH1A1 (0.47) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL64498 0.80 TDP1 (0.54) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL64485 0.79 KDM4E (0.35) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL21277503 0.79 ALDH1A1 (0.41) KDM4EMEN1KMT2ATDP1TSHR
Hydrochloric Acid SCHEMBL1483037 0.77 TDP1 (0.52) KDM4EMEN1KMT2ATDP1TSHR
Hydrochloric Acid SCHEMBL10454907 0.77 TDP1 (0.52) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL2986846 0.74 ALDH1A1 (0.44) TDP1TSHRALDH1A1CASP1CYP3A4
SCHEMBL31141515 0.72 TDP1 (0.48) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL24417902 0.72 ALDH1A1 (0.32) TSHRALDH1A1CASP1CYP3A4
SCHEMBL5175966 0.72 TDP1 (0.48) KDM4EMEN1KMT2ATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330159-B1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS CO LTD (JP) 2013-04-24 EP disclosed
US-8129869-B2 Electret and electrostatic induction conversion device ASAHI GLASS COMPANY, LIMITED (JP) 2012-03-06 US disclosed
US-20110166299-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS COMPANY, LIMITED 2011-07-07 US disclosed
EP-2330159-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE Asahi Glass Company Limited (JP) 2011-06-08 EP disclosed