Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206450 | 0.91 | POLB (0.55) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6204183 | 0.88 | POLB (0.72) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6206629 | 0.85 | POLB (0.56) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6205597 | 0.83 | POLB (0.65) | POLBRAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL6204546 | 0.80 | POLB (0.53) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6206443 | 0.78 | POLB (0.79) | POLBHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6205974 | 0.78 | POLB (0.57) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6204974 | 0.78 | POLB (0.64) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6205372 | 0.77 | POLB (0.55) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5345758 | 0.77 | HPGD (0.56) | POLBHPGDALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |