Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 13/20 | 0.42 |
| ▸ | CTSS | P25774 | 9/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593364 | 1.00 | CA1 (0.45) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL27668563 | 1.00 | CA1 (0.45) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL28409785 | 0.86 | CYP2D6 (0.47) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL7974788 | 0.84 | CA1 (0.44) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL1088544 | 0.83 | CA1 (0.42) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL17596471 | 0.83 | CA1 (0.42) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL18677608 | 0.81 | CA1 (0.41) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL27593370 | 0.80 | CA2 (0.46) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL6684772 | 0.79 | CA1 (0.49) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL9690240 | 0.79 | CA1 (0.40) | CA1CA2CA7CYP2D6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018103058-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE | JANSSEN PHARMACEUTICA NV (BE) | 2018-06-14 | — | — | WO | disclosed |
| CN-101928230-B | Improved synthesis scheme for lacosamide | UCB PHARMA GMBH | 2012-11-07 | — | — | CN | disclosed |
| CN-1989102-B | Improved lacosamide synthesis method | UCB PHARMA GMBH | 2011-04-20 | — | — | CN | disclosed |
| CN-101928230-A | The synthetic method of improved scheme for lacosamide | UCB PHARMA SA | 2010-12-29 | — | — | CN | disclosed |
| CN-1989102-A | Improved lacosamide synthesis method | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-06-27 | — | — | CN | disclosed |
| EP-1546134-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES | ELI LILLY AND COMPANY (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014895-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES | ELI LILLY AND COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |