SCHEMBL6207052

SCHEMBL6207052

CCCCCCCCCCCCCCCCCc1ccccc1C(=O)OO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.54
THRB P10828 1/20 0.54
LMNA P02545 3/20 0.53
TSHR P16473 3/20 0.53
ALDH1A1 P00352 3/20 0.53
LIPG Q9Y5X9 1/20 0.51
PPARA Q07869 3/20 0.51
CYP3A4 P08684 2/20 0.51
MEN1 O00255 1/20 0.51
NR1I2 O75469 1/20 0.51
CHRM2 P08172 1/20 0.51
ADRA2A P08913 1/20 0.51
MAPT P10636 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
KMT2A Q03164 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
TP53 P04637 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6319165 1.00 THRA (0.54) THRATHRBLMNATSHRALDH1A1
SCHEMBL567395 1.00 THRA (0.54) THRATHRBLMNATSHRALDH1A1
SCHEMBL6321066 1.00 THRA (0.54) THRATHRBLMNATSHRALDH1A1
SCHEMBL3640699 1.00 THRA (0.54) THRATHRBLMNATSHRALDH1A1
SCHEMBL6327887 1.00 THRA (0.54) THRATHRBLMNATSHRALDH1A1
SCHEMBL2675369 1.00 THRA (0.54) THRATHRBLMNATSHRALDH1A1
SCHEMBL671316 0.98 TSHR (0.51) THRATHRBLMNATSHRALDH1A1
SCHEMBL27903021 0.97 TSHR (0.50) THRATHRBLMNATSHRALDH1A1
SCHEMBL165358 0.93 TSHR (0.50) THRATHRBLMNATSHRALDH1A1
Methyl Alcohol SCHEMBL28224946 0.92 TSHR (0.49) THRATHRBLMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1223184-B1 Polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 2005-03-30 EP disclosed
EP-1138714-B1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL CO (JP) 2005-02-23 EP disclosed
US-6630562-B2 Radiation and wear resistant molding materials; weatherproofing; mixture with polysiloxane MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-07 US disclosed
US-20020132959-A1 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-09-19 US disclosed
EP-1223184-A1 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-07-17 EP disclosed
US-6340737-B2 COPOLYCARBONATE OF A 9,9-BIS(HYDROXYPHENYL)FLUORENE COMPOUND, A POLYSILOXANE ENDCAPPED WITH A HYDROXYPHENYL GROUP, AND A PHENOLIC DIOL SUCH AS BISPHENOL A; REDUCED OBLIQUE INCIDENCE BIREFRINGENCE, MOLDABILITY, GOOD TRANSPARENCY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-01-22 US disclosed
US-20010039313-A1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-11-08 US disclosed
EP-1138714-A2 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-10-04 EP disclosed