Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.43 |
| ▸ | GALR2 | O43603 | 5/20 | 0.42 |
| ▸ | GALR1 | P47211 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832874 | 0.81 | GALR1 (0.47) | GALR2GALR1MAPT | |
| SCHEMBL5029097 | 0.81 | AGPAT2 (0.53) | PIK3CAAGPAT2GALR2GALR1KCNH2 | |
| SCHEMBL5550587 | 0.77 | GALR1 (0.48) | PIK3CAAGPAT2GALR2GALR1KCNH2 | |
| SCHEMBL6235251 | 0.76 | GALR1 (0.43) | PIK3CAAGPAT2GALR2GALR1KCNH2 | |
| SCHEMBL4839029 | 0.75 | GALR1 (0.46) | PIK3CAAGPAT2GALR2GALR1KCNH2 | |
| SCHEMBL6919919 | 0.74 | AGPAT2 (0.55) | PIK3CAAGPAT2GALR2GALR1TP53 | |
| SCHEMBL6207526 | 0.71 | GALR1 (0.49) | PIK3CAAGPAT2GALR2GALR1 | |
| SCHEMBL4837222 | 0.70 | CCR4 (0.43) | GALR2GALR1CSF1RMAPTGSK3A | |
| SCHEMBL6819099 | 0.70 | GALR1 (0.40) | PIK3CAAGPAT2GALR2GALR1KCNH2 | |
| SCHEMBL5029274 | 0.70 | GALR1 (0.52) | PIK3CAAGPAT2GALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |