Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431931 | 1.00 | MEN1 (0.36) | MEN1KMT2AHRH3L3MBTL1CTSD | |
| SCHEMBL6259042 | 0.88 | HRH3 (0.40) | HRH3CTSDCTSEBACE1BACE2 | |
| SCHEMBL2434825 | 0.88 | HRH3 (0.40) | HRH3CTSDCTSEBACE1BACE2 | |
| SCHEMBL6967287 | 0.83 | HRH3 (0.41) | HRH3CTSDCTSEBACE1BACE2 | |
| SCHEMBL2435439 | 0.81 | KDM4E (0.36) | MEN1KMT2A | |
| SCHEMBL5149942 | 0.78 | HRH3 (0.38) | MEN1KMT2AHRH3L3MBTL1 | |
| SCHEMBL6208688 | 0.78 | HRH3 (0.38) | MEN1KMT2AHRH3L3MBTL1 | |
| SCHEMBL5152963 | 0.75 | GRIN1 (0.37) | L3MBTL1BACE1 | |
| SCHEMBL12571288 | 0.75 | HRH3 (0.43) | HRH3L3MBTL1DDB1CRBN | |
| SCHEMBL7420058 | 0.74 | L3MBTL1 (0.42) | HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189612-A4 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1189612-A1 | VLA-4 INHIBITOR COMPOUNDS | Daiichi Pharmaceutical Co., Ltd. (JP) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000206-A1 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-04 | — | — | WO | disclosed |