Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865316 | 0.84 | CYP19A1 (0.43) | MEN1KMT2AEPHX2CYP19A1CYP17A1 | |
| Ammonia Solution, Strong SCHEMBL4339903 | 0.82 | CYP19A1 (0.42) | MEN1KMT2AEPHX2CYP19A1CYP17A1 | |
| SCHEMBL7150431 | 0.80 | EPHX2 (0.42) | EPHX2HDAC4HDAC1ALDH1A1 | |
| SCHEMBL16534751 | 0.76 | MEN1 (0.41) | MEN1KMT2AMAPK1EPHX2CYP19A1 | |
| SCHEMBL27634517 | 0.75 | CYP19A1 (0.43) | MEN1KMT2AMAPK1EPHX2CYP19A1 | |
| SCHEMBL7914851 | 0.73 | MEN1 (0.39) | MEN1KMT2AMAPK1EPHX2CYP19A1 | |
| SCHEMBL13232360 | 0.73 | CYP19A1 (0.50) | MEN1KMT2AMAPK1EPHX2CYP19A1 | |
| SCHEMBL28927321 | 0.72 | CACNA1H (0.48) | MEN1KMT2AMAPK1EPHX2CYP19A1 | |
| SCHEMBL11991228 | 0.71 | CYP19A1 (0.46) | MEN1KMT2AMAPK1EPHX2CYP19A1 | |
| SCHEMBL21436131 | 0.71 | DGAT1 (0.43) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551844-A2 | ANTITUMORAL ANALOGS OF LAMELLARINS | Pharma Mar, S.A.U. (ES) | 2005-07-13 | — | — | EP | disclosed |
| EP-1532139-A1 | TOTAL SYNTHESIS OF MYRIAPORONES | Pharma Mar, S.A. (ES) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014917-A2 | ANTITUMORAL ANALOGS OF LAMELLARINS | PHARMA MAR, S.A.U. (ES) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004011458-A1 | TOTAL SYNTHESIS OF MYRIAPORONES | PHARMA MAR, S.A.U. (ES) | 2004-02-05 | — | — | WO | disclosed |