SCHEMBL6207800 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	2/20	0.48

▸	HPGD	P15428	2/20	0.48

▸	ALDH1A1	P00352	1/20	0.48

▸	LMNA	P02545	1/20	0.48

▸	P4HB	P07237	1/20	0.48

▸	HSP90AA1	P07900	1/20	0.48

▸	FBP1	P09467	9/20	0.39

▸	HRH4	Q9H3N8	1/20	0.35

▸	POLB	P06746	2/20	0.34

▸	MEN1	O00255	2/20	0.34

▸	KMT2A	Q03164	2/20	0.34

▸	RAB9A	P51151	1/20	0.34

▸	APEX1	P27695	1/20	0.33

▸	XDH	P47989	2/20	0.33

▸	PKM	P14618	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6207805	1.00	KDM4E (0.48)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL5623265	0.93	P4HB (0.47)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL5623259	0.89	P4HB (0.49)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL5624285	0.89	P4HB (0.49)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL6205630	0.89	P4HB (0.49)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL6207810	0.88	KDM4E (0.51)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL6203889	0.87	KDM4E (0.50)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL3560521	0.87	P4HB (0.49)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL3559441	0.87	P4HB (0.48)	KDM4EHPGDALDH1A1LMNAP4HB
SCHEMBL6205186	0.87	P4HB (0.47)	KDM4EHPGDALDH1A1LMNAP4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0938474-B1	CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS	AUCKLAND UNISERVICES LTD (NZ)	2005-11-23	—	—	EP	claimed