Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232837 | 1.00 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL8028251 | 1.00 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL18560091 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL2034664 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL288609 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL203222 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL43380 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL43381 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL203221 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL2034259 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979244-B1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2005-03-02 | — | — | EP | claimed |
| EP-0979244-B1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2005-03-02 | — | — | EP | disclosed |
| EP-0979244-A1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998049193-A1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1998-11-05 | — | — | WO | disclosed |