Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6313316 | 0.97 | MCHR1 (0.61) | MCHR1MEN1KMT2AKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6210165 | 0.92 | MCHR1 (0.66) | MCHR1MAOBKCNH2 | |
| SCHEMBL6186001 | 0.89 | MCHR1 (0.69) | MCHR1MEN1KMT2AKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6208356 | 0.89 | MCHR1 (0.64) | MCHR1MEN1KMT2AKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6208550 | 0.87 | MCHR1 (0.66) | MCHR1MAOBKCNH2 | |
| Trifluoroacetic Acid SCHEMBL6208900 | 0.87 | MCHR1 (0.64) | MCHR1MAOBKCNH2 | |
| Trifluoroacetic Acid SCHEMBL6208461 | 0.87 | MCHR1 (0.64) | MCHR1MAOBKCNH2 | |
| Trifluoroacetic Acid SCHEMBL6188612 | 0.84 | MCHR1 (0.69) | MCHR1MAOBKCNH2 | |
| SCHEMBL6187459 | 0.84 | MCHR1 (0.76) | MCHR1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL6207368 | 0.83 | MCHR1 (0.67) | MCHR1MAOBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534703-A2 | ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR | ABBOTT LABORATORIES (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2003106452-A2 | ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |