Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.61 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6208010 | 0.97 | MCHR1 (0.56) | MCHR1KDM4EMEN1ALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL6210165 | 0.95 | MCHR1 (0.66) | MCHR1ACHEMAOBKCNH2BCHE | |
| SCHEMBL6186001 | 0.93 | MCHR1 (0.69) | MCHR1ACHEKDM4EMEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6208356 | 0.92 | MCHR1 (0.64) | MCHR1ACHEKDM4EMEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6208550 | 0.91 | MCHR1 (0.66) | MCHR1ACHEMAOBKCNH2BCHE | |
| Trifluoroacetic Acid SCHEMBL6208900 | 0.90 | MCHR1 (0.64) | MCHR1ACHEMAOBKCNH2BCHE | |
| Trifluoroacetic Acid SCHEMBL6208461 | 0.90 | MCHR1 (0.64) | MCHR1ACHEMAOBKCNH2BCHE | |
| Trifluoroacetic Acid SCHEMBL6188612 | 0.88 | MCHR1 (0.69) | MCHR1ACHEMAOBKCNH2BCHE | |
| SCHEMBL6187459 | 0.88 | MCHR1 (0.76) | MCHR1ACHEKCNH2CA12CA9 | |
| Trifluoroacetic Acid SCHEMBL6207368 | 0.87 | MCHR1 (0.67) | MCHR1ACHEMAOBKCNH2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921821-B2 | Antagonists of melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885ACHE 3307/4885KDM4E 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.