Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.33 |
| ▸ | PDE1A | P54750 | 4/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5826743 | 0.99 | CRHR1 (0.33) | CRHR1PDE1APDE1BPDE1C | |
| SCHEMBL5826721 | 0.90 | CRHR1 (0.40) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL6209571 | 0.89 | CRHR1 (0.36) | CRHR1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5826904 | 0.88 | CRHR1 (0.35) | CRHR1ALDH1A1HPGD | |
| SCHEMBL5826508 | 0.85 | CRHR1 (0.35) | CRHR1ALDH1A1HPGD | |
| SCHEMBL5826748 | 0.83 | CRHR1 (0.36) | CRHR1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6495482 | 0.82 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL5826408 | 0.76 | CRHR1 (0.34) | CRHR1ALDH1A1HPGD | |
| SCHEMBL5826574 | 0.73 | CRHR1 (0.46) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL5826753 | 0.72 | CRHR1 (0.40) | CRHR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238979-B1 | FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1238979-A1 | FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |