Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742367 | 0.75 | ALDH1A1 (0.39) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL3332979 | 0.75 | GRIN2D (0.33) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL27003067 | 0.75 | ALDH1A1 (0.39) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL5231438 | 0.75 | GRIN2D (0.33) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL26039054 | 0.75 | ALDH1A1 (0.39) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL8510561 | 0.75 | ALDH1A1 (0.39) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29587839 | 0.73 | ALDH1A1 (0.37) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL9853482 | 0.73 | ALDH1A1 (0.37) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL3237003 | 0.72 | ALDH1A1 (0.36) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 | |
| SCHEMBL9853462 | 0.72 | ALDH1A1 (0.36) | GRIN2DGRIN3BCYP2B6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585481-A2 | PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004064721-A2 | A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-08-05 | — | — | WO | disclosed |