Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060488 | 1.00 | KIF11 (0.70) | KIF11KCNH2 | |
| SCHEMBL4058466 | 0.90 | KIF11 (0.74) | KIF11KCNH2 | |
| SCHEMBL4061491 | 0.88 | KIF11 (0.71) | KIF11KCNH2 | |
| SCHEMBL4058593 | 0.88 | KIF11 (0.71) | KIF11KCNH2 | |
| SCHEMBL6205746 | 0.88 | KIF11 (0.71) | KIF11KCNH2 | |
| SCHEMBL4066856 | 0.88 | KIF11 (0.71) | KIF11KCNH2 | |
| SCHEMBL4063362 | 0.88 | KIF11 (0.76) | KIF11KCNH2 | |
| SCHEMBL4062496 | 0.87 | KIF11 (0.70) | KIF11KCNH2 | |
| SCHEMBL6207245 | 0.87 | KIF11 (0.70) | KIF11KCNH2 | |
| SCHEMBL4057816 | 0.87 | KIF11 (0.69) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515724-A4 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1515724-A1 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003105855-A1 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2003-12-24 | — | — | WO | disclosed |