Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208331 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL28473519 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL8885204 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL720263 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL11621023 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL29230428 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL11621018 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL720264 | 1.00 | TP53 (0.45) | TP53ALDH1A1FAAHEPHX2ASAH2 | |
| SCHEMBL1116621 | 0.88 | TERT (0.47) | TP53ALDH1A1FAAHCYP1A2MAPT | |
| SCHEMBL11621021 | 0.88 | TERT (0.47) | TP53ALDH1A1FAAHCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893451-B1 | Polysaccharide modification in densified fluid | NAT STARCH CHEM INVEST (US) | 2005-03-02 | — | — | EP | disclosed |
| US-5977348-A | ESTERIFYING OR ETHERIFYING POLYSACCHARIDE BY MIXING WITH REAGENT UNDER DENSIFIED FLUID UP TO 15% WATER BY VOLUME FOR PERIOD OF TIME; FOR HIGH DEGREE OF SUBSTITUTION WITHOUT USE OF TRADITIONAL ORGANIC SOLVENTS OR REPEATED REACTIONS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0893451-A2 | Polysaccharide modification in densified fluid | National Starch and Chemical Investment Holding Corporation (US) | 1999-01-27 | — | — | EP | disclosed |