Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5826947 | 0.94 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5826529 | 0.91 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL5826791 | 0.90 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5827152 | 0.88 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL5826451 | 0.86 | NPY1R (0.42) | CRHR1 | |
| SCHEMBL5826633 | 0.85 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL5826966 | 0.85 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL5826584 | 0.84 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6209775 | 0.83 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL5826424 | 0.83 | CRHR1 (0.48) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238979-B1 | FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1238979-A1 | FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |