⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945086 | 0.73 | — | — | |
| SCHEMBL19992718 | 0.71 | — | — | |
| SCHEMBL6966410 | 0.71 | — | — | |
| SCHEMBL10789578 | 0.67 | — | — | |
| SCHEMBL21265473 | 0.67 | — | — | |
| SCHEMBL22993177 | 0.67 | — | — | |
| SCHEMBL19781429 | 0.67 | KDM4E (0.37) | — | |
| SCHEMBL20530964 | 0.67 | — | — | |
| SCHEMBL19725155 | 0.67 | — | — | |
| SCHEMBL4351000 | 0.67 | ACHE (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976075-B2 | Inhibitors of the MYST family of lysine acetyl transferases | Isosterix, Inc. | 2024-05-07 | — | — | US | disclosed |
| CN-117412974-A | Salt and crystal form containing pyrazole polycyclic derivative as well as preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| US-20230303580-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2023-09-28 | — | — | US | disclosed |
| EP-3864022-B1 | NEUROACTIVE STEROIDS SUBSTITUTED IN POSITION 10 WITH A CYCLIC GROUP FOR USE IN THE TREATMENT OF CNS DISORDERS | SAGE THERAPEUTICS INC (US) | 2023-09-20 | — | — | EP | disclosed |
| EP-4238971-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2023-09-06 | — | — | EP | disclosed |
| EP-3746451-B1 | BENZYL-, (PYRIDIN-3-YL)METHYL- OR (PYRIDIN-4-YL)METHYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-07-12 | — | — | EP | disclosed |
| EP-3253210-B1 | 2-(HET) ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-11-24 | — | — | EP | disclosed |
| CN-108484613-B | Pyrazolo [1,5-a ] pyrimidine compound and application thereof | 江南大学 | 2020-07-07 | — | — | CN | disclosed |
| WO-2019149657-A1 | BENZYL-, (PYRIDIN-3-YL)METHYL- OR (PYRIDIN-4-YL)METHYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-08-08 | — | — | WO | disclosed |
| CN-108484613-A | A kind of pyrazolo [1,5-a] pyrimidines and its application | 江南大学 | 2018-09-04 | — | — | CN | disclosed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-4039529-A | Cycloaliphatic dicarbonyl containing azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-4017477-A | 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-4014864-A | POLYESTER FIBERS | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3971771-A | DYES FOR POLYESTERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3964862-A | Process for dyeing and printing textile materials of synthetic organic fibers | CIBA-GEIGY AG (CH) | 1976-06-22 | — | — | US | disclosed |
| US-3954398-A | Polyester fibers dyed with a disazo disperse dyestuff | CIBA-GEIGY AG (CH) | 1976-05-04 | — | — | US | disclosed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3933786-A | Heterocyclic-azo-phenyl compounds containing a styrl group | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |