Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072658 | 0.94 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL6072045 | 0.88 | LTB4R2 (0.33) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6072251 | 0.87 | IRAK4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6072382 | 0.86 | — | — | |
| SCHEMBL6072516 | 0.85 | MAPT (0.33) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6072277 | 0.85 | KDM4E (0.34) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6072303 | 0.84 | KDM4E (0.33) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6072142 | 0.84 | IRAK4 (0.30) | — | |
| SCHEMBL6072801 | 0.84 | ALOX5AP (0.34) | — | |
| SCHEMBL6072468 | 0.82 | LMNA (0.32) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541576-A1 | FUROISOQUINOLINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-06-15 | — | — | EP | disclosed |