Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277139 | 0.88 | FLT3 (0.77) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL68771 | 0.85 | FLT3 (0.71) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL3976369 | 0.83 | KDM4E (0.72) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL30381896 | 0.83 | KDM4E (0.72) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL3119090 | 0.81 | FLT3 (0.67) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL2080470 | 0.81 | FLT3 (0.67) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL5957825 | 0.81 | FLT3 (0.61) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL1327116 | 0.80 | FLT3 (0.64) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL31060426 | 0.80 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL370573 | 0.80 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556349-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS 11-BETAHSD1 INHIBITORS | Astrazeneca AB (SE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004033427-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS 11-BETAHSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2004-04-22 | — | — | WO | disclosed |