Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL28840260 | 0.86 | KDM4E (0.57) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL6208710 | 0.85 | FLT3 (0.67) | FLT3KDM4EMAPTDAOHPGD | |
| Quinoline SCHEMBL28161648 | 0.84 | FLT3 (0.53) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL31060426 | 0.83 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL31277139 | 0.83 | FLT3 (0.77) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL1327116 | 0.83 | FLT3 (0.64) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL370573 | 0.83 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL1854127 | 0.83 | KDM4E (0.68) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL4001520 | 0.82 | FLT3 (0.62) | FLT3KDM4EMAPTDAOHPGD | |
| Indole-2-Carboxylic Acid SCHEMBL1935 | 0.82 | KDM4E (1.00) | FLT3KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501166-A | The synthetic method of indoles and norborneol alkanes and its derivative | 南京理工大学 | 2017-12-22 | — | — | CN | claimed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| US-20110262892-A1 | METHODS FOR DETECTION OR MEASUREMENT OF VIRUSES | AOYAGI KATSUMI | 2011-10-27 | — | — | US | claimed |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | claimed |
| EP-0967484-B1 | METHODS FOR DETECTING OR ASSAYING VIRUS | ADVANCED LIFE SCIENCE INST INC (JP) | 2007-05-02 | — | — | EP | claimed |
| US-20060074108-A1 | Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition | BIODERM RESEARCH (US) | 2006-04-06 | — | — | US | claimed |
| EP-0967484-A1 | METHODS FOR DETECTING OR ASSAYING VIRUS | Advanced Life Science Institute, Inc. (JP) | 1999-12-29 | — | — | EP | claimed |
| EP-0827507-B1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM CA LTD (CA) | 1999-06-16 | — | — | EP | claimed |
| US-4175195-A | REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN UNSATURATED KETONE OR ALDEHYDE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-11-20 | — | — | US | claimed |
| US-12331020-B2 | Method of synthesizing indole compounds | 1280225 B.C. LTD. (CA) | 2025-06-17 | — | — | US | disclosed |
| CN-119923256-A | Continuous delivery system comprising cannabinoids and medical uses thereof | 长矛治疗股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119638697-A | ERVITSINE total synthesis method | 南方科技大学 | 2025-03-18 | — | — | CN | disclosed |
| CN-114890947-B | Aromatic heterocyclic compound containing quinoline structural unit, and preparation method and application thereof | 郑州大学 | 2024-07-16 | — | — | CN | disclosed |
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | disclosed |
| US-4873259-A | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0279263-A2 | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |
| CN-85108623-A | Preparation has the novel method of the heterocycleamide of medical active | — | 1986-07-30 | — | — | CN | disclosed |
| EP-0179619-A1 | Heterocyclic amides | ICI AMERICAS INC. (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4175195-A | REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN UNSATURATED KETONE OR ALDEHYDE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-11-20 | — | — | US | disclosed |
| US-4171444-A | REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN ALIPHATIC ALDEHYDE, DEHYDRATING-DEHYDROGENATION CATALYSTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12331020-B2 | Method of synthesizing indole compounds | IDO1, TPH1, TPH2 | FLT3 2429/4885KDM4E 3394/4885MAPT 1116/4885 |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | PSMB1, PLOD3, CUTA | FLT3 4139/4885KDM4E 513/4885MAPT 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.