Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5826424 | 0.78 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5826746 | 0.76 | CRHR1 (0.49) | CRHR1DHFR | |
| SCHEMBL5826970 | 0.76 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL6210405 | 0.74 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL5826968 | 0.73 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL5826925 | 0.73 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL5826520 | 0.73 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5826791 | 0.73 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5826901 | 0.72 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5826881 | 0.72 | CRHR1 (0.42) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238979-B1 | FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1238979-A1 | FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |