Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208869 | 1.00 | HSD17B10 (0.44) | HSD17B10TDP1KDM4EPOLBGLA | |
| SCHEMBL3343392 | 0.87 | FPR1 (0.36) | HSD17B10TDP1POLBHTTMAPT | |
| SCHEMBL3343384 | 0.87 | FPR1 (0.36) | HSD17B10TDP1POLBHTTMAPT | |
| SCHEMBL3347461 | 0.85 | IDO1 (0.43) | HSD17B10TDP1KDM4EPOLBGLA | |
| SCHEMBL4112461 | 0.85 | IDO1 (0.43) | HSD17B10TDP1KDM4EPOLBGLA | |
| SCHEMBL3347473 | 0.85 | IDO1 (0.43) | HSD17B10TDP1KDM4EPOLBGLA | |
| SCHEMBL4112458 | 0.85 | IDO1 (0.43) | HSD17B10TDP1KDM4EPOLBGLA | |
| SCHEMBL3347463 | 0.85 | IDO1 (0.43) | HSD17B10TDP1KDM4EPOLBGLA | |
| SCHEMBL3343593 | 0.79 | HSD17B10 (0.44) | HSD17B10TDP1KDM4EPOLBGLA | |
| SCHEMBL3343602 | 0.79 | HSD17B10 (0.44) | HSD17B10TDP1KDM4EPOLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554250-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031154-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-04-15 | — | — | WO | disclosed |