Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208918 | 1.00 | C1S (0.42) | C1SNAT1 | |
| SCHEMBL6210980 | 0.88 | C1S (0.33) | C1S | |
| SCHEMBL6210638 | 0.87 | SLC9A1 (0.34) | C1S | |
| SCHEMBL6210643 | 0.87 | SLC9A1 (0.34) | C1S | |
| SCHEMBL6209499 | 0.85 | C1S (0.34) | C1S | |
| SCHEMBL5841042 | 0.85 | C1S (0.45) | C1S | |
| SCHEMBL5841048 | 0.85 | C1S (0.45) | C1S | |
| SCHEMBL5840265 | 0.85 | C1S (0.49) | C1S | |
| SCHEMBL5840261 | 0.85 | C1S (0.49) | C1S | |
| SCHEMBL5839748 | 0.84 | C1S (0.47) | C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549632-A4 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | DIMENSIONAL PHARM INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1549632-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |