Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964305 | 0.74 | ALDH1A1 (0.51) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL22536652 | 0.73 | ALDH1A1 (0.51) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL22350095 | 0.72 | ALDH1A1 (0.49) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL12646599 | 0.71 | PTGES2 (0.42) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL1596404 | 0.70 | ALDH1A1 (0.48) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL1593735 | 0.69 | ALDH1A1 (0.66) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL1593925 | 0.68 | ALDH1A1 (0.61) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL13719338 | 0.67 | ALDH1A1 (0.52) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL13471700 | 0.67 | ALDH1A1 (0.60) | ALDH1A1GAAL3MBTL1PTGES2POLB | |
| SCHEMBL12568259 | 0.67 | ALDH1A1 (0.56) | ALDH1A1GAAL3MBTL1PTGES2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | disclosed |