Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | FAP | Q12884 | 4/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042235 | 0.90 | PREP (0.36) | PREPFAPGRNSORT1CTSK | |
| SCHEMBL4045351 | 0.87 | CTSK (0.44) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4043416 | 0.86 | CTSK (0.54) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4039917 | 0.86 | CTSK (0.45) | PREPFAPCTSKCTSLCTSB | |
| SCHEMBL4039168 | 0.85 | CTSK (0.43) | PREPFAPCTSKCCR1 | |
| SCHEMBL4041462 | 0.85 | CTSK (0.54) | PREPFAPCTSKCTSLCTSB | |
| SCHEMBL4042221 | 0.85 | CTSK (0.46) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL6213754 | 0.85 | CTSK (0.40) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4040693 | 0.85 | CTSK (0.44) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4046421 | 0.85 | CTSK (0.42) | PREPFAPCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |