Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL28179788 | 0.92 | ALDH1A1 (0.54) | TP53ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| Ethylbenzene SCHEMBL27517645 | 0.88 | TP53 (0.54) | TP53ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| Ethylbenzene SCHEMBL7596186 | 0.86 | TP53 (0.52) | TP53ALDH1A1TSHRMAOBRAB9A | |
| SCHEMBL10492933 | 0.85 | ALDH1A1 (0.44) | TP53ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| Ethylbenzene SCHEMBL4938574 | 0.83 | TP53 (0.74) | TP53ALDH1A1TSHRMAOBRAB9A | |
| Ethylbenzene SCHEMBL4458040 | 0.83 | TP53 (0.74) | TP53ALDH1A1TSHRMAOBRAB9A | |
| Ethylbenzene SCHEMBL10718712 | 0.83 | TP53 (0.48) | TP53ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| Styrene SCHEMBL468925 | 0.82 | ALDH1A1 (0.64) | TP53ALDH1A1TSHRMAOBRAB9A | |
| Styrene SCHEMBL8030887 | 0.82 | ALDH1A1 (0.64) | TP53ALDH1A1TSHRMAOBRAB9A | |
| Styrene SCHEMBL8161037 | 0.82 | ALDH1A1 (0.64) | TP53ALDH1A1TSHRMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506239-A2 | SURFACE GRAFT MODIFIED RESINS AND FORMATION THEREOF | Phenomenex, Inc. (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003064478-A2 | SURFACE GRAFT MODIFIED RESINS AND FORMATION THEREOF | PHENOMENEX, INC. (US) | 2003-08-07 | — | — | WO | disclosed |