Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212275 | 1.00 | FOLH1 (0.33) | FOLH1CAPN1CTSKCTSBCTSS | |
| SCHEMBL6211048 | 0.78 | NLRP3 (0.33) | — | |
| SCHEMBL8245755 | 0.78 | SCN9A (0.44) | CTSKCTSSSCN9APTPRB | |
| SCHEMBL6747611 | 0.78 | SCN9A (0.44) | CTSKCTSSSCN9APTPRB | |
| SCHEMBL6191559 | 0.77 | CAPN1 (0.40) | FOLH1CAPN1CTSKCTSBCTSS | |
| SCHEMBL6209741 | 0.76 | CYP3A4 (0.36) | — | |
| SCHEMBL6211338 | 0.75 | POLB (0.31) | — | |
| SCHEMBL6212924 | 0.72 | CNR1 (0.44) | FOLH1MAPK1OPRD1 | |
| SCHEMBL6209687 | 0.72 | CNR1 (0.44) | FOLH1MAPK1OPRD1 | |
| SCHEMBL27504467 | 0.71 | FOLH1 (0.33) | FOLH1CAPN1CTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299365-B1 | 2-AMINOTHIAZOLINE DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2005-09-28 | — | — | EP | disclosed |