Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964584 | 0.77 | CNR2 (0.71) | CNR2TACR1S1PR1ALDH1A1USP2 | |
| SCHEMBL5964191 | 0.76 | CNR2 (0.54) | CNR2TACR1S1PR1ALDH1A1USP2 | |
| SCHEMBL5964318 | 0.74 | CNR2 (0.60) | CNR2S1PR1ALDH1A1USP2CYP1A2 | |
| SCHEMBL5964494 | 0.74 | KMT2A (0.45) | CNR2S1PR1ALDH1A1MAPK1ALOX5AP | |
| SCHEMBL1607338 | 0.67 | AKR1B1 (0.42) | PDK2 | |
| SCHEMBL6048540 | 0.66 | CYP2D6 (0.45) | TACR1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22304414 | 0.65 | AR (0.58) | CNR2ALDH1A1USP2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6048557 | 0.65 | CYP2D6 (0.44) | TACR1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8184119 | 0.64 | KIF11 (0.54) | CNR2ALDH1A1TSHRARPDK2 | |
| SCHEMBL24297565 | 0.63 | AR (0.56) | CNR2ALDH1A1USP2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | claimed |