SCHEMBL620943

SCHEMBL620943

CC(C)[Si](C(C)C)(C(C)C)C(C)(C)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20328583 0.69
SCHEMBL620142 0.69 ALDH1A1 (0.32) ALDH1A1CYP2C19
SCHEMBL5925292 0.64
Tert-Butanol SCHEMBL6510107 0.62
SCHEMBL7143844 0.62
Isopropyl Alcohol SCHEMBL9695851 0.62 ALDH1A1 (0.50) ALDH1A1CYP2C19
Isopropyl Alcohol SCHEMBL9695534 0.62
SCHEMBL105298 0.59
SCHEMBL838349 0.59
SCHEMBL2622744 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421873-B1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2014-07-02 EP claimed
US-8182781-B2 Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil GIVAUDAN S.A. (CH) 2012-05-22 US claimed
EP-2421873-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL Givaudan SA (CH) 2012-02-29 EP claimed
US-20120040879-A1 Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil GIVAUDAN SA (CH) 2012-02-16 US claimed
WO-2010121979-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2010-10-28 WO claimed
EP-2421873-B1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2014-07-02 EP disclosed
EP-2421873-B1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2014-07-02 EP disclosed
US-8182781-B2 Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil GIVAUDAN S.A. (CH) 2012-05-22 US disclosed
US-8182781-B2 Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil GIVAUDAN S.A. (CH) 2012-05-22 US disclosed
EP-2421873-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL Givaudan SA (CH) 2012-02-29 EP disclosed
US-20120040879-A1 Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil GIVAUDAN SA (CH) 2012-02-16 US disclosed
US-20120040879-A1 Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil GIVAUDAN SA (CH) 2012-02-16 US disclosed
WO-2010121979-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2010-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040879-A1 Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil FOXK1, S1PR3, CHRM1 ALDH1A1 578/4885CYP2C19 1772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.