Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6209592 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6210024 | 0.80 | — | — | |
| SCHEMBL6208439 | 0.77 | — | — | |
| SCHEMBL6208437 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7083298 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6211542 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7083300 | 0.70 | — | — | |
| SCHEMBL6235849 | 0.67 | — | — | |
| SCHEMBL6236338 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL6287664 | 0.61 | S1PR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848022-B1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | TOTAL PETROCHEMICALS RES FELUY (BE) | 2005-03-02 | — | — | EP | claimed |
| EP-0848022-A1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | FINA TECHNOLOGY, INC. (US) | 1998-06-17 | — | — | EP | claimed |
| US-5753785-A | BUTYLENE-ETHYLENE COPOLYMER | FINA TECHNOLOGY, INC. (US) | 1998-05-19 | — | — | US | claimed |
| EP-0848022-B1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | TOTAL PETROCHEMICALS RES FELUY (BE) | 2005-03-02 | — | — | EP | disclosed |
| EP-0848022-A1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | FINA TECHNOLOGY, INC. (US) | 1998-06-17 | — | — | EP | disclosed |