Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | BCL2 | P10415 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | RPA1 | P27694 | 3/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148951 | 0.88 | MALT1 (0.41) | MDM2MCL1BCL2CHRNA7RPA1 | |
| SCHEMBL14505008 | 0.87 | MDM2 (0.43) | MDM2MCL1BCL2CHRNA7RPA1 | |
| SCHEMBL6210243 | 0.87 | FFAR4 (0.44) | MDM2MCL1BCL2CHRNA7RPA1 | |
| Hydrochloric Acid SCHEMBL5152030 | 0.87 | MDM2 (0.40) | MDM2MCL1BCL2CHRNA7RPA1 | |
| SCHEMBL6208574 | 0.86 | MDM2 (0.41) | MDM2MCL1BCL2CHRNA7RPA1 | |
| SCHEMBL6208572 | 0.85 | MALT1 (0.45) | MDM2MCL1BCL2CHRNA7MALT1 | |
| SCHEMBL6210679 | 0.85 | BCL2 (0.43) | MDM2MCL1BCL2CHRNA7RPA1 | |
| SCHEMBL5148826 | 0.85 | MDM2 (0.43) | MDM2MCL1BCL2CHRNA7RPA1 | |
| SCHEMBL6208556 | 0.83 | FABP3 (0.40) | MDM2MCL1BCL2CHRNA7RPA1 | |
| SCHEMBL14504991 | 0.83 | MDM2 (0.46) | MDM2MCL1BCL2CHRNA7RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050632-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | WO | disclosed |